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Acknowledgments We are grateful for the patients who participated in clinical trials evaluating novel desensitization and AMR therapeutics for their contributions to advancing our understanding of alloimmunity and therapeutic approaches
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The restoration of mTOR signaling with Fer1 rescue treatment in the context of RSL3 effects, and the genetic knockdown of GPX4, reaffirm our in vitro findings that RSL3-mediated induction of ferroptosis, mTOR pathway suppression, DNA damage and failure of DNA repair, and autophagy are GPX4-dependent processes in thyroid cancer cells
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