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Moreover, natural compounds such as andrographolide have been shown to inhibit the RIPK1/RIPK3/MLKL pathway by reducing reactive oxygen species (ROS) generation and preserving mitochondrial integrity, further illustrating the complex interplay between necroptotic signaling and cellular metabolism (105)
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A characteristic feature of ferroptosis is the accumulation of phospholipid hydroperoxides in the presence of catalytically active iron
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