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Because of the lipophilic nature and morphological structure of the membrane, small lipid-soluble substances from the peripheral blood vessels can directly pass through and fuse with the lipid membrane to enter the brain, and small water-soluble drugs can also diffuse through the cellular spaces on the membrane surface to enter the brain
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[DOI] [PMC free article] [PubMed] [Google Scholar] (642).Dong Y
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