glutathione and sulforaphane There are thousands of phytochemicals that upregulate our antioxidant longevity genes—so what makes so special? Sulforaphane upregulates glutathione. Often referred to as “the mother of all antioxidants,” lives up nourishment

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Moreover, a minor proportion of this agent can be metabolized within the liver by the cytochrome P450 enzymes (primarily by CYP2E1) to NAPQI, which is detoxified by conjugation and excreted in the glutathione or NAC forms ( Figure 2 )

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Pregnancy and breastfeeding Small clinical studies suggest that ALA may be safe during pregnancy at doses up to 600mg/day for several weeks, with no serious adverse effects reported.40 However, larger, long-term studies are lacking, and there is no reliable safety data for breastfeeding