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Here's Why Vitamin B Can Cause Rashes, Hives, and Flushing

To reduce bruising, rotate injection sites weekly, allow the pen to reach room temperature before use, ensure the alcohol wipe dries completely before injecting, and apply gentle pressure (without rubbing) for 5–10 seconds after injection

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However, these do have to be prescribed and administered by a healthcare professional, and are more likely to be given to people who have lifelong conditions affecting their ability to absorb B12 or who are at higher risk of consistent deficiency