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New roles for glutathione: Modulators of bacterial virulence and pathogenesis - PMC
During sample collection an assessment as to whether an individual was affected with konzo was conducted following the WHO’s 3 main criteria for diagnosis including evidence of (1) a visible symmetric spastic abnormality of gait while walking or running, (2) a history of onset of less than 1 week followed by a nonprogressive course in a formerly healthy person, and (3) bilaterally exaggerated knee or ankle jerks without signs of disease of the spine
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The mechanism is to promote the GSH levels and reduce MDA, lipid peroxidation, and mitochondrial reactive oxygen ROS (91)
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