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Key safety indicators meet specification, including total heavy metals ≤10 ppm, Pb ≤2 ppm, Hg ≤0.5 ppm, Cd ≤1 ppm, and As ≤3 ppm, with microbiological limits controlled at total plate count ≤1000 cfu/g, yeast and mold ≤100 cfu/g, and E
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This randomized, placebo-controlled, multiple-ascending dose, phase 1b trial aims to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics increasing cagrilintide doses (0.16 – 4.5 mg) vs
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