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Co-enzyme B12 also interacts with the enzyme methionine synthase (5-methyltetrahydrofolate-homocysteine methyltransferase), required for the conversion of homocysteine to methionine, which is essential for folic acid metabolism and the formation of thymine, which is a component of DNA
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A possible explanation for this finding could be that this disease mediates the suppression of gastric acid and may thereby impair the absorption of vitamin B12 from foods [207]
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