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TB-500 promotes angiogenesis (new blood vessel formation), which raises theoretical concerns for individuals with cancer history or risk factors
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Chronic METH exposure reduced acetylated histone H4 levels at the GluA1 , GluA2 , and GluN1 promoters, while increasing HDAC2 and SIN3A binding at GluA1 and GluA2 , suggesting suppressed glutamate receptor expression through epigenetic mechanisms 80
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