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Our results revealed an increase in phosphatidylserine externalization and DNA fragmentation, as well as caspase-3 and caspase-9 activation in CSE-treated ROs compared to controls, suggesting the involvement of the intrinsic apoptotic pathway
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Studies of a mouse model of familial ALS that express human mutant superoxide dismutase 1 (SOD1 G93A ) support a primary role of astrocytes
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