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Indeed, on one hand, CD36 promotes ferroptosis in key anti-tumor immunity cells, CD8 + T lymphocytes, by increasing their uptake of polyunsaturated fatty acids (PUFAs), thereby altering their cytokine production and anti-tumor activity, thus promoting tumor progression [31]
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In diabetes, the role of GSH as an antioxidant molecule is as critical as its contribution in maintaining the levels of GSNO, the main donor of NO, as discussed above
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